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Effect of Silybum marianum extract on hot flash symptoms in postmenopausal wome

Phase 3
Recruiting
Conditions
Hot flashes.
Menopausal and female climacteric states
N95.1
Registration Number
IRCT20190223042811N1
Lead Sponsor
Babol University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
80
Inclusion Criteria

Patients aged 40 to 60 years old. 3 times daily from a previous month.
Individuals who have been treated at least
People who are at least 12 and at most 60 months have passed since the last month. (Menopause)
FSH>40

Exclusion Criteria

Use smoking, Valkel cigarettes.
People with underlying diseases (liver, kidney, metabolic disorders such as thyroid problems) are.
They have a history of sensitivity to herbal medicines.
People who have a history of using anxiolytics, antidepressant, estrogen and progesterone hormones in the last 6 months, use anticoagulant and anti-inflammatory drugs like ibuprofen and other drugs affecting hot flashes.
People who have a history of asthma and allergies.
Pathologic and ultrasonography have been reported in the uterus.
Have a history of mass or malignancy in the breast, ovary or uterus.
Do not have natural blood pressure.
Have a history of thromboembolism.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Hot flashes. Timepoint: At the beginning of treatment, weeks 4 and 8 during treatment and 4 weeks after treatment. Method of measurement: The standard GREEN questionnaire, HFRDIS.;The frequency of hot flashes. Timepoint: At the beginning of treatment, weeks 4 and 8 during treatment and 4 weeks after treatment. Method of measurement: Daily Inventory of Hot flashes.
Secondary Outcome Measures
NameTimeMethod
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