The comparison of intravenous dexamethasone and paracetamol in the prevention of post Dural puncture headache in elective cesarean section under spinal anesthesia

Phase 2

• Conditions: cesarean.; Newborn (suspected to be) affected by Cesarean delivery; P03.4

• Registration Number: IRCT20141009019470N80
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 August 2019

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 290

Inclusion Criteria

ASA I-II
Minimum NPO time = 8 hours
Elective cesarean section

Exclusion Criteria

Spinal anesthesia
Contraindications of Local infection in the lumbar region (spinal cord needle entry site)
Use anti-platelet and anticoagulant
Sensitivity to Local anesthesia
Diabetes mellitus
kidney Diseases
Renal failure
Coagulation disorder
Liver disease
Heart disease
History of seizure or any neurological disease
Migraine and pressure headaches
The history of drug addiction
Failure of spinal anesthesia or multiple attempts to perform spinal anesthesia more than once
Systolic blood pressure above 150 and less than 100
Preeclampsia
IUGR
The lack of proper growth of the uterus
Weight above 100
Height less than 150 and more than 180 cm
Hemoglobin less than 8
Caesarean section more than 3 times
Sensitivity to dexamethasone and paracetamol

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Headache. Timepoint: At the arrival to the recovery room and after discharge from the recovery room at 6,12,24,48,72 hr. Method of measurement: Visual Analog Score.

Secondary Outcome Measures

Name	Time	Method
Incidence of Nausea and Vomiting. Timepoint: At the arrival to the recovery room and after discharge from the recovery room at 6,12,24,48,72 hr. Method of measurement: Observasion.