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Clinical Trials/NCT01332045
NCT01332045
Completed
Not Applicable

Continuous Saphenous Nerve Block (Adductor Channel) and Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty

Henning Lykke Andersen1 site in 1 country40 target enrollmentApril 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain, Postoperative
Sponsor
Henning Lykke Andersen
Enrollment
40
Locations
1
Primary Endpoint
Pain scores
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

Our study will compare the use of continuous saphenous nerve block performed at the adductor canal in addition to Local Infiltration Analgesia (LIA) versus a Sham block in addition to LIA for total knee replacement. The investigators hypothesize that the saphenous nerve block performed at the level of the adductor canal in addition to LIA provides better pain relief than the LIA alone without significantly compromising muscle strength and physiotherapy, enabling patients to mobilize early with reduced opioid consumption and les side effects.

The investigators will enroll a total of 40 patients (20 patients will receive continuous saphenous nerve block in addition to LIA and 20 will receive the sham block and LIA). Until discharge, the investigators will record patients' pain scores, opioid consumption, side effects and physical therapy progress.

If our study proves that the continuous saphenous nerve block in addition to LIA can effectively reduce postoperative pain scores to an acceptable level with better physical therapy progress and less opioid consumption, it could be seen as a more attractive alternative to LIA alone or other traditionally used methods of postoperative pain control that compromises muscle strength and physiotherapy.

Registry
clinicaltrials.gov
Start Date
April 2011
End Date
January 2012
Last Updated
14 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Henning Lykke Andersen
Responsible Party
Sponsor Investigator
Principal Investigator

Henning Lykke Andersen

Consultant

Frederiksberg University Hospital

Eligibility Criteria

Inclusion Criteria

  • ASA I-III
  • Age: 40-75
  • Unilateral TKA
  • Use of Spinal anesthesia

Exclusion Criteria

  • Allergy to any of the study medications
  • Intolerance to morphine
  • Contraindication to a spinal anesthetic
  • Intraoperative use of any volatile anesthetic
  • Chronic opioid use
  • ASA Class 4-5
  • Rheumatoid arthritis or Diabetes mellitus with neuropathy
  • Liver or kidney failure
  • BMI above 40
  • Severe COPD

Outcomes

Primary Outcomes

Pain scores

Time Frame: 3 days postoperative

VAS pain scores

Secondary Outcomes

  • physical therapy progress(3 days postoperative)
  • Opioid consumption(3 days postoperative)

Study Sites (1)

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