Role of Injection Dexamethasone in Post extubation Stridor
Not Applicable
- Conditions
- Health Condition 1: J399- Disease of upper respiratory tract, unspecified
- Registration Number
- CTRI/2023/01/048701
- Lead Sponsor
- ady Hardinge Medical College and Kalawati Saran Children Hospital, New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children aged 1 months to 18 years requiring mechanical ventilation for more than 48 hours and planned for extubation
Exclusion Criteria
Pre-existing upper airway anomalies
Previous tracheal intubation or tracheostomy
Contraindications for steroid therapy (Upper GI Bleed, Hypertension, hyperglycemia)
Children who had previously received steroids for more than 7 days (I.e. Patients on steroid therapy)
Previous extubation failure during PICU stay
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of children who developed post extubation stridor in children receiving mechanical ventilation for more than 48 hoursTimepoint: mechanical ventilation for more than 48 hours
- Secondary Outcome Measures
Name Time Method Proportion of children developing side effects due to IV dexamethasone in both the groupsTimepoint: mechanical ventilation for more than 48 hours;Proportion of patients requiring adrenaline neb and reintubation following extubationTimepoint: mechanical ventilation for more than 48 hours;Risk factors for development of post extubation stridorTimepoint: mechanical ventilation for more than 48 hours;Time to recovery from post extubation stridor/ post extubation airway obstruction in both the groupsTimepoint: mechanical ventilation for more than 48 hours