Effect of Probiotic Intake on Improvement of Higher Cerebral Function in Participants with Suspected Mild Cognitive Impairment

Not Applicable

• Conditions: Healthy subjects

• Registration Number: JPRN-UMIN000031679
• Lead Sponsor: HUMA R&D CORP

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-04-04
• Study Completion: 2018-07-27
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Not provided

Exclusion Criteria

1) Subjects who are under medication or treatment for serious disease. 2) Subjects who are under diet therapy and exercise therapy in the control of doctor. 3) Subjects with a history of liver disease or serious renal, endocrine, cardiovascular, gastrointestinal, pulmonary, hematological and metabolic diseases or those who undertake medication or treatment for such disease. 4) Subjects having a history of major surgery involving gastrectomy, gastrointestinal suture surgery, bowel resection, digestive system etc. (except fo rappendicitis) 5) Subjects with a current or past history of psychiatric disorders. 6) Subjects with a current or past history of drug or food allergy. 7) Subjects who are diagnosed as dementia. 8) Subjects who are receiving or have a history of drug dependence or drug abuse. 9) Subjects who have participated in other clinical tests within the past one months. 10) Subjects with irregular working hours, such as night shifts. 11) Subjects with a current or past history of alcoholism. 12) Subjects who were judged inadequate by investigator for other reasons.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
RBANS MMSE

Secondary Outcome Measures

Name	Time	Method
POMS2(Short Form) Patient Health Questionnaire-9 (PHQ-9)