CTRI/2025/03/081739尚未招募不适用
Does Aspirin enhance the regenerative capacity of L-PRF Block in the treatment of intrabony defects. A parallel design, double arm, non-inferiority randomized clinical trial
DR ATHIYA FATHIMA A1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2025年3月16日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- RADIOGRAPHIC PARAMETER OF VERTICAL DEFECT ON CBCT
研究概览
简要总结
To evaluate the clinical and radiographic outcomes of Open Flap Debridement with L-PRF block.
To evaluate the clinical and radiographic outcomes of Open Flap Debridement with L-PRF Block and Aspirin.
To comparatively evaluate the clinical and radiographic outcomes of Open Flap Debridement with L-PRF Block, with or without the addition of Aspirin in the treatment of intrabony vertical defects
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •STAGE 3 GRADE A PERIODONTITIS PATIENTS BOP More than 15% bleeding sites.
- •Minimum of 20 teeth, excluding third molars to be present.
- •Patients with good general health.
- •Non-smokers.
排除标准
- •Any systemic or debilitating disease affecting periodontal and bone health (e.g., Diabetes).
- •Immunocompromised patients (HIV infected).
- •Regular anti-inflammatory medication use (NSAIDS or Aspirin).
- •Regular intake of any medication that affects bone metabolism (vitamin D supplements).
- •Antimicrobial use in the last three months.
- •Surgical periodontal treatment in the last six months.
- •Endodontically treated teeth.
- •Allergy to aspirin.
结局指标
主要结局
RADIOGRAPHIC PARAMETER OF VERTICAL DEFECT ON CBCT
时间窗: BASELINE (0 MONTH) | 6 MONTHS
次要结局
- Gingival index ( Loe and Silness 1963)(Plaque index (Turesky-Gilmore-Glickman modification of Quigley Hein plaque index 1970))
研究者
DR ATHIYA FATHIMA A
BANGALORE INSTITUTE OF DENTAL SCIENCES
研究点 (1)
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