Umbilical Cord-derived Mesenchymal Stem Cell Exosomes on Hair Growth in Patients With Androgenetic Alopecia
- Conditions
- Androgenic Alopecia
- Interventions
- Registration Number
- NCT06697080
- Lead Sponsor
- Nanfang Hospital, Southern Medical University
- Brief Summary
A total of 50 patients with androgenetic alopecia were selected for the study. Patients who met the inclusion/exclusion criteria were randomly assigned to groups A and B in a 1:1 ratio to receive treatment, with the enrollment date designated as Day 1. Group A visited the clinic once each in the first, second, and third months for treatment with exosomes, while Group B visited the clinic twice each in the first, second, and third months for treatment with exosomes. At the time points of 1, 2, 3, and 6 months after the start of the treatment period, dermatoscopic examinations were conducted on patients in both groups. The differences in hair growth density, hair shaft thickness, and follicle counts within a 1 cm diameter area were compared between the two groups. Additionally, the data differences for each subject at baseline and at the end of the experiment were also assessed.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 50
Clinical diagnosis of Androgenic alopecia · AGA classification include：The No grade for male hair loss was II-V, and the Ludwig grade for female hair loss was I-III
(1) Using medications or supplements, including finasteride, dutasteride, minoxidil or any other hormonal products, that can affect hair growth; · (2) Patients with severe diseases, immune diseases, endocrine diseases and nervous system diseases; (3) Patients with infection, allergic disease and malignant tumor
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group B Human umbilical cord mesenchymal stem cells Group B visited the clinic twice each in the first, second, and third months for treatment with exosomes. Group A Human umbilical cord mesenchymal stem cells Group A visited the clinic once each in the first, second, and third months for treatment with exosomes
- Primary Outcome Measures
Name Time Method hair diameters changed over time 0 days, 1 month, 3 months, 6 months hair diameters changed over time
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Plastic and Aesthetic Surgery, Nanfang Hospital Southern 8 Medical University
🇨🇳Guangzhou, Guangdong, China