The Effects of Ultrasound-guided Mid-point Transverse Process to Pleura Block, Erector Spinae Plane Block and Paravertebral Block on Postoperative Pain in Video-assisted Thoracic Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- postoperative morphine consumption
研究概览
简要总结
Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia. This study is to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.
详细描述
Ultrasound-guided nerve block is an important part of multi-mode analgesia to decrease the consumption of opioids. Thoracic paravertebral block is considered as an ideal regional analgesic choice for video-assisted thoracic surgery, but it still has some side effects, such as pneumothorax, vascular injury, especially for novices. Recent years, ultrasound-guided mid-point transverse process to pleura block and erector spinae plane block are reported for thoracic surgery. The insertion depth in these two methods is more superficial than traditional paravertebral block. They could have less side effects. Therefore, we design a randomised control study to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •selective lobetomy under VATS
- •ASA classfication 1-3
排除标准
- •history of thoracic surgery
- •double lateral VATS
- •allergy to local anesthetics
- •coagulation disorders
- •severe heart diseases, hepatic or renal insufficiency
- •a history of chronic pain or chronic opioid use
- •psychiatric disease or uncooperative
- •BMI>28 kg/m2
- •VATS transfered to open thoractomy
结局指标
主要结局
postoperative morphine consumption
时间窗: postoperative 24 hours
The dose is according to the record from PCA pump
次要结局
- Pain score at rest(at 0, 8, 24 hour after surgery)
- Pain score while coughing(at 0, 8, 24 hour after surgery)
研究者
Wenlong Yao
Associate Professor
Huazhong University of Science and Technology