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Clinical Trials/NCT04829409
NCT04829409
Unknown
N/A

The Effects of Ultrasound-guided Mid-point Transverse Process to Pleura Block, Erector Spinae Plane Block and Paravertebral Block on Postoperative Pain in Video-assisted Thoracic Surgery

Huazhong University of Science and Technology1 site in 1 country90 target enrollmentApril 5, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Thoracic Anesthesia
Sponsor
Huazhong University of Science and Technology
Enrollment
90
Locations
1
Primary Endpoint
postoperative morphine consumption
Last Updated
4 years ago

Overview

Brief Summary

Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia. This study is to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.

Detailed Description

Ultrasound-guided nerve block is an important part of multi-mode analgesia to decrease the consumption of opioids. Thoracic paravertebral block is considered as an ideal regional analgesic choice for video-assisted thoracic surgery, but it still has some side effects, such as pneumothorax, vascular injury, especially for novices. Recent years, ultrasound-guided mid-point transverse process to pleura block and erector spinae plane block are reported for thoracic surgery. The insertion depth in these two methods is more superficial than traditional paravertebral block. They could have less side effects. Therefore, we design a randomised control study to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.

Registry
clinicaltrials.gov
Start Date
April 5, 2021
End Date
December 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Wenlong Yao

Associate Professor

Huazhong University of Science and Technology

Eligibility Criteria

Inclusion Criteria

  • selective lobetomy under VATS
  • ASA classfication 1-3

Exclusion Criteria

  • history of thoracic surgery
  • double lateral VATS
  • allergy to local anesthetics
  • coagulation disorders
  • severe heart diseases, hepatic or renal insufficiency
  • a history of chronic pain or chronic opioid use
  • psychiatric disease or uncooperative
  • BMI\>28 kg/m2
  • VATS transfered to open thoractomy

Outcomes

Primary Outcomes

postoperative morphine consumption

Time Frame: postoperative 24 hours

The dose is according to the record from PCA pump

Secondary Outcomes

  • Pain score at rest(at 0, 8, 24 hour after surgery)
  • Pain score while coughing(at 0, 8, 24 hour after surgery)

Study Sites (1)

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