A clinical trial to study effect of Dexamethasone on duration of analgesia(pain relief) in brachial plexus block by Bupivacaine(local anaesthetic)
Phase 3
- Conditions
- Other specified injuries of elbowand forearm,
- Registration Number
- CTRI/2020/03/023757
- Lead Sponsor
- IAF
- Brief Summary
Brachial plexus block is one of the preferred techniques for anaesthesia for upper limb surgeries. The advantage being that of analgesia lasting even after the anaesthesia with motor block wears off. Many adjuvants have been explored for co-administration along with the local anaesthetic to prolong this period. Each of these adjuvants has its own side effect profile, with this study we will attempt at understanding the analgesic effect and duration and also the side effect profile by comparing blood sugar levels and duration of motor blockade.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
- Posted for Open Reduction Internal Fixation of UpperLimb fractures 2.
- Upper limb surgery where Supraclavicular brachial plexus block is indicated.
Exclusion Criteria
- Weight less than 40 Kg 2.
- Pregnancy 3.
- Poor sensorium (GCS < 13) 4.
- Contraindications to Dexamethasone 5.
- Diabetes Mellitus 6.
- Patients on current steroid therapy or within past 6 weeks.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Compare the duration of Analgesia of brachial plexus block and time to first additional analgesic Measured over 48 hours
- Secondary Outcome Measures
Name Time Method Duration of motor weakness of arm measured every 6 hours Measured over 48 hours Postoperative blood sugar every 6 hours Measured over 48 hours
Trial Locations
- Locations (1)
Air Force Hospital
🇮🇳Dehat, UTTAR PRADESH, India
Air Force Hospital🇮🇳Dehat, UTTAR PRADESH, IndiaAditya SapraPrincipal investigator9680019684adityasapra@gmail.com