Testosterone Replacement Therapy Decreases Plasma Paraoxonase 1 Enzyme Activity In Male Patients With Hypogonadism

Phase 4

Completed

• Conditions: Hypogonadism
• Interventions: Drug: Sustanon

• Registration Number: NCT01107067
• Lead Sponsor: Gulhane School of Medicine

Brief Summary

The purpose of this study is investigating the effect of testosterone treatment on paraoxonase level in male patients with hypogonadotrophic hypogonadism

Detailed Description

Not available

Study Timeline

• Status Verified: 2008-05
• Study Start: 2008-06
• Primary Completion: 2009-12
• Study Completion: 2009-12
• Study First Submitted: 2010-04-19
• Study First Submitted QC: 2010-04-19
• Last Update Submitted: 2010-04-19
• Study First Posted: 2010-04-20
• Last Update Posted: 2010-04-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 32

Inclusion Criteria

• Volunteers patients with hypogonadism

Exclusion Criteria

• Coronary heart disease
• Other pituitary/hypothalamic disorders or other non-hypogonadism diseases
• None was receiving vitamins, lipid-lowering drugs, or other medications known to interfere with PON1 activity, lipid profile, or gonadal function

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
testosterone replacement therapy	Sustanon	-

Primary Outcome Measures

Name	Time	Method
paraoxonase level after testosterone treatment

Trial Locations

Locations (1)

Aydoğan AYDOĞDU; 🇹🇷 Ankara, Turkey