DRKS00031138招募中Unknown
Pruritus in systemic diseases- Cohort with Myeloproliferativeneoplasms (MPN) - PruSearch MP
niklinik Aachen0 个研究点目标入组 60 人开始时间: 2023年1月26日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- N/a: Single Arm Study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 one(—)
- 性别
- All
入选标准
- •Diagnosis of a Bcr Abl negative Myeloproliferative Neoplasm according to WHO criteria
- •-patients with systemic pruritus (NRS = 3) or Low-itch control group NRS <3 (NRS<3 lasting for more than 6 weeks)
- •- Caucasian with skin type I-IV
- •- Written informed consent
排除标准
- •- Severe neurological or psychiatric disorders, which may harm the understanding of the informed consent or a lack of linguistic understanding, reading disabilities or disabilities in sight.
- •- No consent for registration, storage or processing of personal data
- •- No consent for biomaterial donation incl. skin biopsy
- •- Chronic pruritus due to other diseases than MPN (e.g. medical eruption,
- •psychogenic pruritus)
- •- Pregnancy or breastfeeding
- •- Neurologic diseases (e.g. Multiple sclerosis, Parkinson's disease, epilepsy) or other diseases, which may affect the study examinations (e.g. HIV infection; pacemaker or implanted defibrillator)
- •- Skin lesions (e.g. acute injury, acid burn, cutane injuries in the biopsy region
- •- Tendency to abnormal scarring
- •- Known allergic reaction to local anesthetics, plaster or latex
研究者
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