Role of regional block (Infraorbital nerve block) in conjunction with general anaesthesia for intra-operative haemodynamic management and post-operative pain control in patients undergoing Pituitary Surgery.
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/07/055385
- Lead Sponsor
- Dr Kanika Gupta
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients in the age group 18-65 years
Patients belonging to ASA-I/II category
Patients planned to undergo elective trans-nasal trans-sphenoidal pituitary surgery
Exclusion Criteria
Known allergy to study drug
Refusal to participate in study
Inability to comprehend or adhere to study protocol
GCS < 15
Pregnancy
Faciomaxillary deformities
BMI >40kg/m2
Known allergy to NSAIDs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first rescue analgesiaTimepoint: Visual analogue scale for pain assessment at the time of extubation, 1st hour, 4th hour, 8th hour, 12th hour and 24th hour postoperatively
- Secondary Outcome Measures
Name Time Method To compare intra-operative haemodynamic fluctuations between the two groups <br/ ><br>To compare emergence from anaesthesia between the two groups <br/ ><br>To compare post-operative analgesia using VAS scores between the two groups <br/ ><br>To compare post-operative analgesic requirement for 24 hours after surgery between the two groupsTimepoint: Assessment of Blood pressure & heart rate at 1 min & 5 min of induction, at the time of infraorbital nerve block, 5 min after block & every 10 min henceforth till 60 min <br/ ><br>Assessment of Ramsay agitation sedation score 1 min after extubation, 10 min, 30 min after extubation, 1st, 2nd & 4th hour after extubation <br/ ><br>Assessment of time to first rescue analgesia if VAS score is more than or equal to 4 <br/ ><br>