Oxygen Delivery in CPAP and Its Relationship With Regional Lung Ventilation in Preterm Infants
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Inspired Oxygen
研究概览
简要总结
With this study, it is expected to learn more about preterm babies on breathing support with nasal continuous positive airway pressure (nCPAP). To gain more information on how much oxygen is actually delivered to the baby from the nCPAP machine.
详细描述
This study will tell more about a specific method of breathing support used frequently with preterm babies called nasal continuous positive airway pressure (nCPAP). It helps the baby breathe by providing air pressure and a certain amount of oxygen. It is very important for the baby's health to provide only as much oxygen as they need.
With this study, it is expected to learn if the amount of oxygen ordered by a doctor on the nCPAP machine changes when it reaches the baby's airway, and if the amount of oxygen changes depending on how much air pressure the doctor provides. The answers to these questions, are not known, because special measurements are required that are difficult to know while a baby is on nCPAP. This study will collect these special measurements
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Gestational age at birth must be less than 35 weeks of completed gestation as documented in the subject's initial history and physical
- •The infant must be stable while receiving nasal CPAP at any pressure level at the time of study
- •The infant must be receiving 22-40% at the time of the study
排除标准
- •Oxygen requirements greater than 40% at time of enrollment
- •currently receiving invasive ventilation or not requiring ventilatory support
- •Major congenital anomalies of the heart and/or lungs
结局指标
主要结局
Inspired Oxygen
时间窗: Sampling will occur at three separate points within a thirty minute time frame for each enrolled infant.
Percent of oxygen delivered to the back of the infant's mouth. This will be measured by placing a small plastic tube in the back of the infant's mouth and sampling the air while the infant is receiving several different pressure levels of CPAP.
次要结局
- Lung Volume(Long volume will be continuously monitored throughout the 30 minute duration of the study for each enrolled infant.)