Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome
- Conditions
- Chronic Obstructive Pulmonary DiseaseObstructive Sleep Apnea
- Interventions
- Diagnostic Test: CPET
- Registration Number
- NCT01033266
- Lead Sponsor
- University of Oklahoma
- Brief Summary
Nasal CPAP will improve cardiopulmonary exercise test (CPET) performance in patients with overlap syndrome(COPD and OSA). Nasal CPAP is proven to improve cardiopulmonary exercise testing in patients with OSA. The investigators hypothesis is that patients with overlap syndrome will have a greater improvement in their cardiopulmonary exercise testing besides a possible improvement in their lung function test and airway resistance.
- Detailed Description
Patients presenting to the Oklahoma City VA sleep clinic with obstructive sleep apnea syndrome and a desire to initiate CPAP treatment will be included if they have overlap syndrome. Patients will undergo a spirometry and CPET before being started on CPAP as part of standard clinical care. The CPET will be repeated after 8-12 weeks of CPAP use. Patients will be excluded if they have any contraindication to mild exercise or they cannot perform an exercise test due to limited mobility.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 12
- Obstructive sleep apnea (OSA)
- COPD
- Inability to perform exercise test due to musculoskeletal limitation
- Cardiac condition preventing patient from mild exercise
- Continuous oxygen supplement
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description CPET CPAP CPET -
- Primary Outcome Measures
Name Time Method Efficacy of nasal CPAP on CPET performance in patients with overlap syndrome 2 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
VA Medical Center
🇺🇸Oklahoma City, Oklahoma, United States
OU Medical Center
🇺🇸Oklahoma City, Oklahoma, United States