Clinical study of minimally invasive embedding in the treatment of knee osteoarthritis

Phase 1

• Conditions: knee osteoarthritis

• Registration Number: ITMCTR2000003733
• Lead Sponsor: ongHua Hospital Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1.Patients who meet the diagnostic criteria of Western medicine and traditional Chinese medicine of KOA;
2.The age is between 18 and 75 years old;
3.Joint function grade II and above (ACR standard);
4.Kellgren & Lawrence grade 2 and above;
5.Patients who agree and sign informed consent;
6.Patients who have not been treated with traditional Chinese and Western medicine or other therapies for knee osteoarthritis in recent 1 month.

Exclusion Criteria

1.Allergy and scar constitution;
2.Acute joint injury knee joint tuberculosis tumor, rheumatoid osteoarthritis and so on;
3.Patients with osteogenic ankylosis due to significant narrowing of joint space or formation of bone bridge connection between joints;
4.Patients with obvious varus deformity of knee joint and history of vascular and nerve injury in affected limb;
5.Patients with cardiovascular, cerebrovascular, liver, kidney, hematopoietic system and other serious diseases, diabetic psychosis;
6.Pregnant and lactating women;
7.Patients who have used relevant treatment drugs or failed to stop using other treatment methods in recent 1 month.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
WOMAC scale;VAS score;WHOQOL-BREFscale;

Secondary Outcome Measures

Name	Time	Method
adverse event;