Low Salt Diet in Idiopathic Hypercalciuria
- Conditions
- Hypercalciuria
- Interventions
- Behavioral: Water therapy aloneBehavioral: Low salt diet
- Registration Number
- NCT01005082
- Lead Sponsor
- University of Parma
- Brief Summary
Randomized clinical trial comparing water therapy plus low-salt diet to water therapy alone in patients affected by idiopathic calcium nephrolithiasis.
Treatment duration: three months Primary end-point: correction of hypercalciuria Main inclusion criteria: calcium stone formers with idiopathic hypercalciuria, with at least one stone expelled and analyzed by infrared spectrophotometry; presence of hypercalciuria (\>300 mg/day in males and \>200 mg/day in females); 18-65 years.
Main exclusion criteria: primary hyperparathyroidism, primary hyperoxaluria, enteric hyperoxaluria, bowel resection, inflammatory bowel disease, renal tubular acidosis, sarcoidosis, sponge kidney, hyperthyroidism, use of hypercalciuric drugs such as Vitamin D, acetazolamide, anti-epileptic drugs
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 210
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description water therapy alone Water therapy alone - Low salt diet plus water therapy Low salt diet -
- Primary Outcome Measures
Name Time Method Normalization of urinary calcium levels
- Secondary Outcome Measures
Name Time Method Change in urinary stone risk factors (e.g. urinary calcium, oxalate and sodium excretion); blood pressure reduction
Trial Locations
- Locations (1)
University Hospital
🇮🇹Parma, Italy