Sustained infections under substitution of IgG (Immunoglobuline G)

• Conditions: D83.0; Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function

• Registration Number: DRKS00010561
• Lead Sponsor: niversitätsklinikum FreiburgCentrum für Chronische Immundefizienz (CCI)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-05-25
• Study Completion: 2016-12-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

diagnosis of PID (primary immunodeficiency) with antibody deficiency,
male and female patients,
18 years,
understanding of German language,
informed consent available

Exclusion Criteria

no

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of persistent infection suceptibility despite immunoglobuline substitution therapy

Secondary Outcome Measures

Name	Time	Method
•Willingness of patients with persistent infection susceptibility in spite of standard immunoglobulin substitution therapy (intravenous or subcutanous) to receive an alternative intravenous immunoglobuline supportive therapy with one- or two-weekly application<br><br>•Association of persistent infection susceptibility in spite of immunoglobulin substitution therapy with reduced IgM and IgA serum level<br><br><br>