A Retrospective Study on the Effectiveness and Safety of Macrogol 4000, Sodium Chloride, Sodium Bicarbonate, and Potassium Chloride in Pregnant Women with Chronic Constipatio
- Conditions
- Chronic Constipation
- Registration Number
- JPRN-UMIN000046499
- Lead Sponsor
- Juntendo University Nerima Hospital Department of Obstetrics and Gynecology
- Brief Summary
The administration of macrogol preparations to pregnant women with chronic constipation resulted in a significant increase in the frequency of bowel movements 4 weeks after administration , and the effect continued until 8 weeks. In addition, chronic constipation symptoms such as straining and stool hardness improved after 4 weeks, and the effect continued until the end of treatment. Adverse events, side effects and safety issues were not confirmed.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 36
Not provided
Patients who have history of Macrogol allergies Patiants who have presence or suspicion of Intestinal obstruction , Intestinal perforation, Severe Inflammatory bowel disease(Ulcerative colitis, Crohn's disease, toxic megacolon) Patiants who have presence or suspicion of organic constipation Patients who received the Macrogol preparation outside the approved dosage and administration
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method