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Clinical Trials/NCT05308641
NCT05308641
Active, not recruiting
Not Applicable

Effectiveness of Radial Extracorporeal Shockwave Therapy in Patients With Chronic Low Back Pain - Randomized Controlled Trial

Ruhr University of Bochum1 site in 1 country400 target enrollmentSeptember 18, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Low-back Pain (cLBP)
Sponsor
Ruhr University of Bochum
Enrollment
400
Locations
1
Primary Endpoint
change in Numeric Rating Scale (NRS)
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

Analysis of the effectiveness of radial shock wave therapy as part of a multimodal pain therapy in the inpatient setting. Different therapy protocols are compared in previously non-operated and in previously operated patients.

Detailed Description

Radial shock wave therapy is an approved pain therapy procedure that has been used in various degenerative orthopedic diseases for years. There are a few studies on the subject of chronic back pain. Some studies suggest that this method can be used sensibly. A direct comparison of different therapy protocols has not been carried out so far. As part of inpatient multimodal pain therapy (including infiltration and physiotherapy) in patients with chronic lumbar back pain with or without degenerative surgery in the area of the lumbar spine radial shock wave therapy after a specific protocol is used. Only inpatients will be admitted to the study. All patients are informed verbally and give their written consent. Comprehensive patient information will be provided before the start of the study, handed out and explained as part of the information discussion. There will be 2 groups ((a) patients with previous degenerative surgery in the area of the lumbar spine, (b) patients without such a pre-operation) examined each with 4 sub-groups depending of the different therapy protocols.

Registry
clinicaltrials.gov
Start Date
September 18, 2022
End Date
December 7, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Ruhr University of Bochum
Responsible Party
Principal Investigator
Principal Investigator

Dr. med. Tobias Lange, MBA

Principal Investigator

Ruhr University of Bochum

Eligibility Criteria

Inclusion Criteria

  • chronic lumbar back pain of min 3 months duration

Exclusion Criteria

  • radicular pain of higher intensity than chronic low back pain (cLBP)
  • new neurologic deficits
  • anticoagulant therapy
  • new trauma to the lumbar spine
  • spine bacterial infection
  • spine tumor
  • pregnancy
  • coagulation disorder
  • previous infiltration to the lumbar spine within 6 weeks prior to study inclusion
  • fibromyalgia

Outcomes

Primary Outcomes

change in Numeric Rating Scale (NRS)

Time Frame: pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Pain intensity measured by Numeric Rating Scale (NRS) - 11-point scale / min. 0 (better outcome) / max. 10 (worse outcome)

Secondary Outcomes

  • change in Oswestry Disability Index (ODI)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)
  • change in Patient Health Questionnaire-9 (PHQ-9)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)
  • change in Perseverative Thinking Questionnaire (PTQ)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)
  • change in Patient Specific Functional Scale (PSFS)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)
  • change in Questionnaire Subgroups for Targeted Treatment (STarT-G)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)
  • change in European Quality of Life 5 Dimensions (EQ5D)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)
  • change in Pain Self-Efficacy Questionnaire (PSEQ)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)
  • change in The World Health Organisation- Five Well-Being Index (WHO-5)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)
  • change in Big Five Inventory-SocioOeconomicPanel (BFI-S)(pre-intervention, 2 weeks, 1 month, 3 months, 6 months)

Study Sites (1)

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