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Effectiveness of Radial Extracorporeal Shockwave Therapy in Patients With Chronic Low Back Pain

Not Applicable
Active, not recruiting
Conditions
Chronic Low-back Pain (cLBP)
Interventions
Procedure: standard multimodal pain therapy
Procedure: radial extracorporeal shockwave therapy_500_2
Procedure: radial extracorporeal shockwave therapy_4000_20
Registration Number
NCT05308641
Lead Sponsor
Ruhr University of Bochum
Brief Summary

Analysis of the effectiveness of radial shock wave therapy as part of a multimodal pain therapy in the inpatient setting. Different therapy protocols are compared in previously non-operated and in previously operated patients.

Detailed Description

Radial shock wave therapy is an approved pain therapy procedure that has been used in various degenerative orthopedic diseases for years. There are a few studies on the subject of chronic back pain. Some studies suggest that this method can be used sensibly. A direct comparison of different therapy protocols has not been carried out so far.

As part of inpatient multimodal pain therapy (including infiltration and physiotherapy) in patients with chronic lumbar back pain with or without degenerative surgery in the area of the lumbar spine radial shock wave therapy after a specific protocol is used. Only inpatients will be admitted to the study. All patients are informed verbally and give their written consent. Comprehensive patient information will be provided before the start of the study, handed out and explained as part of the information discussion. There will be 2 groups ((a) patients with previous degenerative surgery in the area of the lumbar spine, (b) patients without such a pre-operation) examined each with 4 sub-groups depending of the different therapy protocols.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
400
Inclusion Criteria
  • chronic lumbar back pain of min 3 months duration
Exclusion Criteria
  • radicular pain of higher intensity than chronic low back pain (cLBP)
  • new neurologic deficits
  • anticoagulant therapy
  • new trauma to the lumbar spine
  • spine bacterial infection
  • spine tumor
  • pregnancy
  • coagulation disorder
  • previous infiltration to the lumbar spine within 6 weeks prior to study inclusion
  • fibromyalgia

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
PrevSurg_NO/rESWT_nostandard multimodal pain therapyPrevious Surgery on degenerative pathology in lumbar spine: NO rESWT: no
PrevSurg_NO/rESWT_4000standard multimodal pain therapyPrevious Surgery on degenerative pathology in lumbar spine: NO rESWT: 4000 pulse, 20 Hz
PrevSurg_YES/rESWT_500standard multimodal pain therapyPrevious Surgery on degenerative pathology in lumbar spine: YES rESWT: 500 pulse, 2 Hz
PrevSurg_YES/rESWT_denystandard multimodal pain therapyPrevious Surgery on degenerative pathology in lumbar spine: YES rESWT: denied
PrevSurg_YES/rESWT_500radial extracorporeal shockwave therapy_500_2Previous Surgery on degenerative pathology in lumbar spine: YES rESWT: 500 pulse, 2 Hz
PrevSurg_YES/rESWT_nostandard multimodal pain therapyPrevious Surgery on degenerative pathology in lumbar spine: YES rESWT: no
PrevSurg_NO/rESWT_4000radial extracorporeal shockwave therapy_4000_20Previous Surgery on degenerative pathology in lumbar spine: NO rESWT: 4000 pulse, 20 Hz
PrevSurg_NO/rESWT_500radial extracorporeal shockwave therapy_500_2Previous Surgery on degenerative pathology in lumbar spine: NO rESWT: 500 pulse, 2 Hz
PrevSurg_NO/rESWT_500standard multimodal pain therapyPrevious Surgery on degenerative pathology in lumbar spine: NO rESWT: 500 pulse, 2 Hz
PreviousSurgery(PrevSurg)_YES/rESWT_4000radial extracorporeal shockwave therapy_4000_20Previous Surgery on degenerative pathology in lumbar spine: YES rESWT: 4000 pulse, 20 Hz
PreviousSurgery(PrevSurg)_YES/rESWT_4000standard multimodal pain therapyPrevious Surgery on degenerative pathology in lumbar spine: YES rESWT: 4000 pulse, 20 Hz
PrevSurg_NO/rESWT_denystandard multimodal pain therapyPrevious Surgery on degenerative pathology in lumbar spine: NO rESWT: denied
Primary Outcome Measures
NameTimeMethod
change in Numeric Rating Scale (NRS)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Pain intensity measured by Numeric Rating Scale (NRS)

- 11-point scale / min. 0 (better outcome) / max. 10 (worse outcome)

Secondary Outcome Measures
NameTimeMethod
change in Oswestry Disability Index (ODI)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Oswestry Disability Index (ODI)

change in Patient Health Questionnaire-9 (PHQ-9)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Patient Health Questionnaire-9 (PHQ-9)

change in Perseverative Thinking Questionnaire (PTQ)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Perseverative Thinking Questionnaire (PTQ)

change in Patient Specific Functional Scale (PSFS)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Patient Specific Functional Scale (PSFS)

* five daily important activities are rated on a 11-point scale

* min. 0 (worse outcome) / max. 10 (better outcome)

change in Questionnaire Subgroups for Targeted Treatment (STarT-G)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Subgroups for Targeted Treatment (STarT-G)

change in European Quality of Life 5 Dimensions (EQ5D)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

European Quality of Life 5 Dimensions (EQ5D)

change in Pain Self-Efficacy Questionnaire (PSEQ)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Pain Self-Efficacy Questionnaire (PSEQ)

change in The World Health Organisation- Five Well-Being Index (WHO-5)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

The World Health Organisation- Five Well-Being Index (WHO-5)

change in Big Five Inventory-SocioOeconomicPanel (BFI-S)pre-intervention, 2 weeks, 1 month, 3 months, 6 months

Big Five Inventory-SocioOeconomicPanel (BFI-S)

Trial Locations

Locations (1)

Klinik Blankenstein

🇩🇪

Hattingen, Germany

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