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临床试验/JPRN-UMIN000036506
JPRN-UMIN000036506已完成未知

Optimization of Immunomodulators and Their Withdrawal After Achievement of Mucosal Healing in Long-term Maintenance of Quiescent Ulcerative Colitis - Optimization of Immunomodulators and Their Withdrawal After Achievement of Mucosal Healing in Long-term Maintenance of Quiescent Ulcerative Colitis

Dokkyo Medical University, Department of Gastroenterology.0 个研究点目标入组 89 人开始时间: 2019年4月14日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
89

研究概览

简要总结

A significantly higher remission maintenance rate was observed in the IM continuation group (p??<??0.01). No significant difference was observed between the IM continuation group with a WBC of less than 3000 or a MCV of 100 or greater and the IM continuation group with a WBC of 3000 or greater and a MCV of 99 or lower (p??=??0.08). Higher remission maintenance rates were observed in the IM continuation group of patients for whom MH had been achieved (p??=??0.03).

研究设计

研究类型
Observational

入排标准

年龄范围
10years-old 至 85years-old(—)
性别
All

入选标准

  • 未提供

排除标准

  • Of the 283 cases, a case where remission had not been achieved within 1 year of the oral administration of immunomodulators, a case with a history of anti-TNF alfa antibody agent administration, a case with less than 80% adherence to immunomodulators were excluded.

研究者

发起方
Dokkyo Medical University, Department of Gastroenterology.

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