The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance
Not Applicable
- Conditions
- Inflammation
- Interventions
- Dietary Supplement: resveratrol
- Registration Number
- NCT01244360
- Lead Sponsor
- Marywood University
- Brief Summary
The purpose of this study is to examine the effects of resveratrol on health and human performance. The study will evaluate cognitive function and several indicators of physical health before and after taking a resveratrol supplement or a placebo for three weeks.
- Detailed Description
Measurements
* blood laboratory parameters
* cognitive assessment changes
* body composition changes
* vascular endothelial response
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
- men and women between 45 and 75 years of age
- Normal heart rate and Blood pressure
- Ability to use personal computer interface
- Successful completion of physical activity readiness questionnaire
Exclusion Criteria
- Cardiovascular disease, uncontrolled hypertension, lung disease
- inability to tolerate exercise
- have taken grape related supplement in past 12 months
- current use of drugs or dietary supplements to enhance exercise performance
- allergy to wine, grape juice or grape seed supplements
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Dietary Supplement: resveratrol resveratrol Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.
- Primary Outcome Measures
Name Time Method Vascular function 4 weeks, with option of additional 4 week treatment period vascular response to stress will be measured using flow mediated dilation and ultrasound.
- Secondary Outcome Measures
Name Time Method Body fat percentage 4 weeks, with optional additional 4 week treatment period Body fat percentage will be measured using a DEXA scan.
inflammation biomarkers 4 weeks, with optional additional 4 week treatment period Fasting blood draw
cognitive function 4 weeks, with optional additional 4 week treatment period cognitive function will be assessed using a validated computer based assessment tool
Trial Locations
- Locations (1)
Marywood University
🇺🇸Scranton, Pennsylvania, United States