ITMCTR2000003560
Recruiting
Phase 1
Effects of combined transcutaneous electrical acupoint stimulation and general anesthesia on postoperative cognitive function in geriatric patients undergoing thoracoscopic radical resection for lung cancer
The Second Affiliated Hospital of Air Force Medical University (Tangdu Hospital)0 sitesTBD
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- The Second Affiliated Hospital of Air Force Medical University (Tangdu Hospital)
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\)Patients are scheduled for thoracoscopic radical resection for lung cancer which may last more than 2 hours;
- •2\)Patients aged 65–90 years;
- •3\)BMI: 18\-30kg/?;
- •4\)American Society of Anesthesiologists status I to III;
- •5\)Primary tumor, never had radiotherapy or chemotherapy before;
- •6\)Conduct pulmonary sequestration with a double\-lumen tube;
- •7\)Patients are voluntary to sign informed consent form.
Exclusion Criteria
- •1\)Patients with communication disorders such as language comprehension disorder, mental disorders, epilepsy, history of Parkinson's disease or myasthenia Gravis and so on;
- •2\)History of opioid, alcohol or other drug abuse and addiction;
- •3\)Patients with TEAS contraindications including partial damaged skin, infection or implantable internal electrophysiologic device;
- •4\)History of unstable angina pectoris or myocardial infarction within 3 months; NYHA \>\= III;
- •5\)Pre\-existing hypertension (systolic pressure \>\= 180 mmHg and/or diastolic pressure \>\= 110 mmHg), WHO\-ISH III;
- •6\)Patients with pre\-existing complications of diabetes such as diabetic ketoacidosis, diabetic hyperosmolar coma, kinds of infections, macroangiopathy, nephrosis, retinopathy, diabetic cardiopathy, diabetic neuropathy, diabetes feet and so on;
- •7\)Patients with hepatic and renal insufficiency (Severe abnormality of hepatic function: Of ALT, CB, AST, ALP and TB, one if is twice more than the normal upper limit; Severe abnormality of renal function: Cr \< 30 ml/min, Scr \> 177umol/L);
- •8\)COPD: GOLD III or IV, Lung fibrosis, Uncontrolled asthma;
- •9\)History of pulmonary operation;
- •10\)Unilateral pulmonary resection or bilateral pulmonary operation;
Outcomes
Primary Outcomes
Not specified
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