ITMCTR2000003560招募中1 期
Effects of combined transcutaneous electrical acupoint stimulation and general anesthesia on postoperative cognitive function in geriatric patients undergoing thoracoscopic radical resection for lung cancer
The Second Affiliated Hospital of Air Force Medical University (Tangdu Hospital)0 个研究点开始时间: 待定最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 65 至 90(—)
- 性别
- All
入选标准
- •1)Patients are scheduled for thoracoscopic radical resection for lung cancer which may last more than 2 hours;
- •2)Patients aged 65–90 years;
- •3)BMI: 18-30kg/?;
- •4)American Society of Anesthesiologists status I to III;
- •5)Primary tumor, never had radiotherapy or chemotherapy before;
- •6)Conduct pulmonary sequestration with a double-lumen tube;
- •7)Patients are voluntary to sign informed consent form.
排除标准
- •1)Patients with communication disorders such as language comprehension disorder, mental disorders, epilepsy, history of Parkinson's disease or myasthenia Gravis and so on;
- •2)History of opioid, alcohol or other drug abuse and addiction;
- •3)Patients with TEAS contraindications including partial damaged skin, infection or implantable internal electrophysiologic device;
- •4)History of unstable angina pectoris or myocardial infarction within 3 months; NYHA >= III;
- •5)Pre-existing hypertension (systolic pressure >= 180 mmHg and/or diastolic pressure >= 110 mmHg), WHO-ISH III;
- •6)Patients with pre-existing complications of diabetes such as diabetic ketoacidosis, diabetic hyperosmolar coma, kinds of infections, macroangiopathy, nephrosis, retinopathy, diabetic cardiopathy, diabetic neuropathy, diabetes feet and so on;
- •7)Patients with hepatic and renal insufficiency (Severe abnormality of hepatic function: Of ALT, CB, AST, ALP and TB, one if is twice more than the normal upper limit; Severe abnormality of renal function: Cr < 30 ml/min, Scr > 177umol/L);
- •8)COPD: GOLD III or IV, Lung fibrosis, Uncontrolled asthma;
- •9)History of pulmonary operation;
- •10)Unilateral pulmonary resection or bilateral pulmonary operation;
- •11)Massive hemorrhage in operation;
- •12)Taking pulmonary sequestration ways such as difficult airway, tracheotomy, occluder, artificial pneumothorax excluded DLT ;
- •13)Patients took part in other clinical trials within 3 months;
- •14)The physician in charge or the researcher considers that patients with other inappropriate circumstances in this study (reasons should be recorded).
研究者
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