The Effect on Time After Extubation on Aspiration Risk
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 71
- Locations
- 1
- Primary Endpoint
- Severity of Aspiration per Evaluation
Study Overview
Brief Summary
The investigators hypothesize that aspiration will be more prevalent at two to four hours post-extubation but will resolve in the majority of patients by 24 to 26 hours post-extubation.
The purpose of the research is to investigate whether there is a difference in swallow function two to four hours after extubation (removal of breathing tube) compared to 24 hours after extubation. This information will help healthcare providers decide if it is necessary for people to wait 24 hours after extubation before they start eating and drinking.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients that were intubated for more than 48 hours.
- •Adults, 18 and over
- •All races
- •Males and females
- •Approval to participate in the study by the treating physician
Exclusion Criteria
- •Patients with a history of oropharyngeal dysphagia.
- •Patients with neurological disorders associated with dysphagia including dementia, Parkinson's disease, multiple sclerosis, stroke, and ALS.
- •Patients with a history of head and neck cancer or laryngeal surgery.
- •Patients that are not candidate for FEES because of facial fractures, nothing by mouth (NPO) status for other procedures, elevated bleeding risk (patients on therapeutically dosed anticoagulant infusion or injection, platelet count less than 50,000, INR greater than 2.0, partial thromboplastin time greater than 1.5 times normal), decreased level of arousal/alertness, significant agitation, or inability to tolerate room air or nasal cannula oxygen for duration of FEES.
- •Patients who are extubated after 1400 or on weekends (Friday, Saturday, or Sunday).
- •Non-English Speakers will be excluded
Outcomes
Primary Outcomes
Severity of Aspiration per Evaluation
Time Frame: post-extubation at 2-4 hours and possibly 24-26 hours.
Flexible Endoscopic Evaluation of Swallow (FEES - a measure of swallowing which will allow for the diagnosis of swallowing) will be recorded at between 2 to 4 hour after extubation. If penetration/aspiration is noted during the evaluation between 2 to 4 hours post-extubation, then a second FEES evaluation will be completed between 24 to 26 hours post-extubation.
Secondary Outcomes
No secondary outcomes reported