The involvement of mesalazine concentration in colonic mucosa of patients with ulcerative colitis under treatment with oral mesalazine
Not Applicable
- Conditions
- lcerative Colitis
- Registration Number
- JPRN-UMIN000011455
- Lead Sponsor
- Department of Gastroenterology and Hepatology, Kyoto University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1:UC patients who were treated with pentasa enema or salazosulfapyridine suppository 2:Patients with rectal sparing 3:Patients who have a contraindication against mesalazine 4:Patients with severe renal failure 5:Patients with severe hepatic failure 6:Patients treated with prokinetic agents 7:Concomitant malignancies 8:Patients after gastrectomy 9:Under 20 year-old 10:no agreement for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method concentration measurement of colinic mesalazine
- Secondary Outcome Measures
Name Time Method 1:Clinical activity index (partial UC-DAI) 2:Endoscopic findings 3:Safety