MedPath

Efficacy of Alprazolam on blood pressure control

Phase 2
Recruiting
Conditions
Essential (primary) hypertension.
Essential (primary) hypertension
Registration Number
IRCT20220423054624N1
Lead Sponsor
Shahroud University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
94
Inclusion Criteria

Systolic blood pressure over 180 or Diastolic blood pressure over 110
age between 18-80 years old
Ability to understand and sign the conscientious informed consent
No previous Allergy to Captopril or Alprazolam

Exclusion Criteria

Left Acute Heart Failure
Chronic Renal Failure
Cardiovascular disease
History of stroke
History of myocardial infraction
Taking other Benzodiazepines in the last week
Taking Muscle Relaxant drugs such as Baclofen
Taking anti-anxiety drugs from other group such as Buspirone or Zolpidem
Pregnant and Lactating women
Occurring an emergency situation which indicates prescribing other Antihypertensive drug based on the Doctor's diagnosis
Patients who have more than 15 mmHg difference in blood pressure between arms .

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Systolic and diastolic blood pressure. Timepoint: checking blood pressure at the beginning of the study and then at 30 ,60 , 90 and 120 minutes after the intervention. Method of measurement: using a clinical mercury manometer device for monitoring the blood pressure in a standardized manner in which patient is lying down.
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath