Gut Microbiota and Stool Frequency

Completed

• Conditions: Gut Microbiota
• Interventions: Other: Stool frequency

• Registration Number: NCT03153059
• Lead Sponsor: Kosin University Gospel Hospital

Brief Summary

We hypothesized that some difference in the composition and distribution of gut microbiota in people with a large number of defecation (two or three times a day or more), people with normal defecation (one time a day or two days), and people with a small number of defecation (two times a week or less).

And we investigate the association between gut microbiota and stool frequency.

Detailed Description

We divided three groups. (total number = 60 subjects)

1. a large number of defecation group (≥ 2-3 times/day) - 20 subjects

2. normal defecation group (1 time/day or 1 time/2 days) - 20 subjects

3. a small number of defecation group (≤ 2 times/week) - 20 subjects

After collection of stools, we will analyze the composition and distribution of gut microbiota, and compared the results of three groups.

Study Timeline

• Study Start: 2017-05-11
• Study First Submitted: 2017-05-11
• Study First Submitted QC: 2017-05-11
• Study First Posted: 2017-05-15
• Primary Completion: 2017-09-30
• Study Completion: 2017-10-30
• Status Verified: 2017-12
• Last Update Submitted: 2017-12-01
• Last Update Posted: 2017-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• adults between the age of 20 and 50

Exclusion Criteria

• subjects with cancer or IBD (inflammatory bowel disease)
• subjects with history of abdominal surgery
• subjects who take medication related to gastrointestinal motility within 3 months
• subjects who take antibiotics within 3 months

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
group 2	Stool frequency	normal defecation group (1 time/day or 1 time/2 days) - 20 subjects
group 3	Stool frequency	a small number of defecation group (≤ 2 times/week) - 20 subjects
group 1	Stool frequency	a large number of defecation group (≥ 2-3 times/day) - 20 subjects

Primary Outcome Measures

Name	Time	Method
stool frequency and gut microbiota	six months	Analysis of correlation between stool frequency and gut microbiota

Secondary Outcome Measures

Name	Time	Method
stool consistency and gut microbiota	six months	Analysis of correlation between stool consistency and gut microbiota

Trial Locations

Locations (1)

Kosin University Gospel Hospital; 🇰🇷 Busan, Korea, Republic of