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临床试验/NCT04165746
NCT04165746
招募中
不适用

Early Institutionalization Intervention Impact Project

Boston Children's Hospital1 个研究点 分布在 1 个国家目标入组 220 人2023年3月16日

概览

阶段
不适用
干预措施
Caregiving Intervention
疾病 / 适应症
Socioemotional Development
发起方
Boston Children's Hospital
入组人数
220
试验地点
1
主要终点
Differences in security of attachment
状态
招募中
最后更新
上个月

概览

简要总结

The purpose of this study is to determine the effects of early intervention (placement into foster care, and a caregiving training) on physical, cognitive, social and brain development and psychiatric symptomatology in children place in out-of-home care.

详细描述

The Early Institutionalization Intervention Impact (EI-3) Project will document and compare the impact of enhanced institutional care on early childhood development to that of high-quality foster care. We will recruit a large (n= 220) samples of young children who have been identified as having to be removed from their families and we will randomize these children to two groups: enhanced institutional care (Group 1) or to enhanced foster care (Group 2). Institutional caregivers and Foster Parents will participate in a caregiving training, along with the child, that includes 8-1.5 hour sessions over 8-9 weeks. In this Randomized Control Trial (RCT), we will assess the children in Groups 1 and 2 at the time they come into care and then at several follow-up time points (12 months, 24 months, 36 months of age). We hypothesize that children placed into foster/family care (FCG) will display enhanced socioemotional development, and enhanced behavioral and neural patterns of attention, cognition and social cognition, compared to children placed in enhanced institutional care.

注册库
clinicaltrials.gov
开始日期
2023年3月16日
结束日期
2029年3月31日
最后更新
上个月
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Principal Investigator
主要研究者

Charles Alexander Nelson III

Richard David Scott Chair in Pediatric Developmental Medicine Research, Professor of Pediatrics and Neuroscience

Boston Children's Hospital

入排标准

入选标准

  • newly entering the institution system in and near São Paulo, Brazil, and the institution director or foster parent is the guardian at the time of baseline,
  • at the time of baseline assessment the child is less than 24 months old,
  • the child's birth weight must be at or above 2500 grams; none should be small or large for dates.

排除标准

  • the child does not have a neurological or other genetic condition that severely impairs typical development (e.g. Cerebral Palsy, Fetal Alcohol Syndrome, Down Syndrome)
  • the child is below 2500 grams.

研究组 & 干预措施

Enhanced Institutional Care

Caregivers at institutions will participate in a caregiving training, called Attachment VideoFeedback Intervention (AVI). During AVI a trained interventionist meets with a caregiver and child in the home environment. The AVI Interventionist will meet with caregivers and children for 8, 1.5-hours sessions over 8-9 weeks to discuss recordings of children and their caregivers. As described above, the sessions will focus on creating a positive atmosphere by reinforcing positive interactions.

干预措施: Caregiving Intervention

Enhanced Foster Care

Foster parents will be recruited, consented to background checks, and trained in Portuguese. Hired foster parents will supported and monitored by project social workers and psychologists from local Foster Care programs. Foster parents will received frequent visits from the social workers, with visits occurring weekly for several months after placement of the child, then biweekly and later monthly. Project social workers will consult weekly with US staff experienced in dealing with young children in foster care. Additionally, foster parents will participate in the VIPP caregiving training, in the same format as that described in the Enhanced Institutional Care Arm: the VIPP Interventionist will meet with caregivers and children for 5, 2-hours sessions over 6-8 weeks to discuss recordings of children and their caregivers. As described above, the sessions will focus on creating a positive atmosphere by reinforcing positive interactions.

干预措施: Foster Care

Enhanced Foster Care

Foster parents will be recruited, consented to background checks, and trained in Portuguese. Hired foster parents will supported and monitored by project social workers and psychologists from local Foster Care programs. Foster parents will received frequent visits from the social workers, with visits occurring weekly for several months after placement of the child, then biweekly and later monthly. Project social workers will consult weekly with US staff experienced in dealing with young children in foster care. Additionally, foster parents will participate in the VIPP caregiving training, in the same format as that described in the Enhanced Institutional Care Arm: the VIPP Interventionist will meet with caregivers and children for 5, 2-hours sessions over 6-8 weeks to discuss recordings of children and their caregivers. As described above, the sessions will focus on creating a positive atmosphere by reinforcing positive interactions.

干预措施: Caregiving Intervention

结局指标

主要结局

Differences in security of attachment

时间窗: baseline, 12 mos, 24 mos, 36 mos

Strange Situation Procedure

Differences in Alpha Electroencephalogram (EEG) Power, Coherence and Functional Connectivity

时间窗: baseline, 12 mos, 24 mos, 36 mos

EEG power

次要结局

  • Differences in Competence(baseline, 12 mos, 24 mos, 36 mos)
  • Differences in Cognition in early Childhood(baseline, 12 mos, 24 mos, 36 mos)
  • Differences in Attachment Disturbances and Disorders(baseline, 12 mos, 24 mos, 36 mos)

研究点 (1)

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