Dysrhythmias During General Anesthesia in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 234
- 试验地点
- 1
- 主要终点
- Arrhythmias During General Anesthesia in Children
研究概览
简要总结
To describe the types and incidence of cardiac dysrhythmias that occur under anesthesia in the present anesthesia environment.
详细描述
It is unclear what the current state of anesthesia associated dysrhythmias is in the pediatric population. This was last investigated retrospectively in 1992 when the predominant volatile agent used for inhalation induction was halothane. Sevoflurane was approved by the Food and Drug Administration in 1995. Since that time, Sevoflurane has displaced halothane as the agent of choice for inhalation induction and has relegated halothane to be used in a narrow niche which primarily involves patients with very specific congenital heart diseases. It has been described that halothane has a larger proarrhythmic effect than sevoflurane for ventricular dysrhythmias. With the transition from the halothane to the sevoflurane era, a reassessment of the incidence and types of dysrhythmias occurring in non-cardiac pediatric patients is important.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children, while under anesthesia, having
- •circumstances of tachycardia and bradycardia,
- •administration of medications used in the treatment of dysrhythmias,
- •the commentary which includes comment about the heart rhythm or therapy for dysrhythmia,
- •in the quality assurance database for evidence of dysrhythmia
排除标准
- •Children with a known pre-operative:
- •prior history of dysrhythmia and/or
- •residual congenital heart disease
- •anti/pro dysrhythmic medications
结局指标
主要结局
Arrhythmias During General Anesthesia in Children
时间窗: July 1998 through July 2004
次要结局
未报告次要终点