Evaluating the effects of oral dextromethorphan in acute pain after surgery in patients undergoing vitrectomy
Not Applicable
Recruiting
- Conditions
- Condition 1: Disorders of vitreous body. Condition 2: postprocedural pain.Disorders of vitreous bodyPain during the period after surgery.G89.18
- Registration Number
- IRCT2017102510599N21
- Lead Sponsor
- Vice-Chancellor of research Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
all patients between 35 to 75 years old; with ASA classes I and II; undergoing vitrectomy under general anesthesia;
Exclusion criteria: Obese patients; History of opioid consumption within 48 hours of surgery; sedatives or centrally acting drugs use (central nervous system depressants or antidepressants) 21 days prior to surgery; those with a history of chronic pain; psychotic disorders or addiction including opioids; those with any contraindications to dextromethorphan; and pregnant or lactating women.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: after surgery in recovery, 1, 2 and 6 hours after surgery. Method of measurement: using visual analogue scale.
- Secondary Outcome Measures
Name Time Method Sedation rate. Timepoint: after surgery in recovery, 1, 2 and 6 hours after surgery. Method of measurement: using Ramsy sedation assessment scale.