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Comparison of NovoFine® Needles (4 mm vs. 6 mm)

Phase 2
Completed
Conditions
Diabetes Mellitus, Type 1
Diabetes
Diabetes Mellitus, Type 2
Delivery Systems
Registration Number
NCT00343343
Lead Sponsor
Novo Nordisk A/S
Brief Summary

This trial is conducted in Europe. The aim of this investigation is to explore the safety of a 4 mm needle compared to a 6 mm needle when injected in children and lean adults with diabetes.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
62
Inclusion Criteria
  • Children
  • Type 1 diabetes
  • Insulin treatment for more than ½ year
  • BMI lesser than or equal to 19 kg/m2
  • Last HbA1c taken within the last year lesser than 10.5%
  • Girls: only prepubertal
  • Boys: both pre pubertal and pubertal. Adults
  • Type 1 and 2 diabetes
  • Insulin treatment for more than ½ year
  • BMI lesser than or equal to 23 kg/m2
  • Last HbA1c taken within the last year lesser than 10.5%
Exclusion Criteria
  • Known or suspected allergy to trial product(s) or related products.
  • Pregnant, breast-feeding or the intention of becoming pregnant or not using adequate contraceptive measures (including country-specific adequate measures, if any).
  • Skin disease at abdomen and/or thigh

Study & Design

Study Type
INTERVENTIONAL
Study Design
FACTORIAL
Primary Outcome Measures
NameTimeMethod
Deposition of sterile air depositions.
Secondary Outcome Measures
NameTimeMethod
Amount of backflow
Thickness of 1) dermis and 2) distance from skin surface to muscle fascia

Trial Locations

Locations (1)

Novo Nordisk Investigational Site

🇩🇰

Århus C, Denmark

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