To find the relation between various blood parameters and functioning of heart in ST elevation myocardial infarction patients.

Not yet recruiting

Brief Summary: India has the highest burden of Acute Coronary Syndrome (ACS) patients in the world. Indian Patients who suffer from ACS are relatively younger and have a significantly higher proportion of ST-elevation myocardial infarction (STEMI) as compared to patients in developed countries. It is estimated that more than 3 million STEMI occurs every year in India. The measurement of left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI) is a class I clinical practice guideline recommendation, and has both prognostic and therapeutic implications. Reduced LVEF is associated with greater mortality in patients with coronary artery disease and predicts increased risks of early mortality, as well as sudden cardiac death. Serum ferritin is an acute phase reactant and is considered to be a risk factor for MI. High serum ferritin may increase the risk of MI in the presence of other risk factors that increase the formation of free radicals, thus accelerating atherogenesis through stimulation of low-density lipoprotein oxidation. So, the aim of the study is to find the correlation of troponin I and ferritin levels with left ventricular ejection fraction in ST elevation MI patients presenting to the hospital.

Recruitment & Eligibility

Inclusion Criteria

Exclusion Criteria

1.Previous history of myocardial infarction.
2.A patient having pre existing ECG changes s/o old MI or ECG showing Q wave at the time of admission.
LVH, conduction defects, heart blocks.
Conditions in which Troponin I levels increases irrespective of heart disease.: renal impairment, rheumatoid arthritis, pericarditis, spesis, acute congestive heart failure, acute pulmonary embolism, or prolonged tachyarrythmias.
Hemochromatosis, liver disease, TB, patients on iron supplements.

Primary Outcome Measures

Name	Time	Method
Troponin I levels	baseline
S. ferritin levels	baseline
Left ventricular ejection fraction	baseline

Secondary Outcome Measures

Name	Time	Method
Correlation OF S. ferritin & troponin I levels along with their correlation with left ventricular ejection fraction	baseline

Locations (1): Guru Gobind Singh Medical College and Hospital, Faridkot.
🇮🇳
Faridkot, PUNJAB, India
Guru Gobind Singh Medical College and Hospital, Faridkot.
🇮🇳Faridkot, PUNJAB, India
Dr Lovish Batheja
Principal investigator
7777800027
lovishbatheja@gmail.com