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Gastrointestinal behavior of tenofovir DF in healthy volunteers

Phase 1
Conditions
healthy volunteers (administration of antiviral drug)
Therapeutic area: Diseases [C] - Virus Diseases [C02]
Registration Number
EUCTR2011-005863-25-BE
Lead Sponsor
Katholieke Universiteit Leuven - Pharmacotechnology and Biopharmacy
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
5
Inclusion Criteria

- healthy volunteers
- age between 18 and 35
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 10
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- pregnancy
- disease
- use of medication
- regular exposure to X-radiation last year

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main Objective: To evaluate the gastrointestinal behavior and absorption of tenofovir DF.;Secondary Objective: - To compare absorption of tenofovir DF with or without co-medication <br>- To compare fasted versus fed state.;Primary end point(s): not applicable;Timepoint(s) of evaluation of this end point: not applicable
Secondary Outcome Measures
NameTimeMethod
Secondary end point(s): not applicable;Timepoint(s) of evaluation of this end point: not applicable
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