The Effect of Virtual Reality Exercises on Patients With Post-COVID-19 Condition

Not Applicable

Completed

• Conditions: Covid19

• Registration Number: NCT04983394
• Lead Sponsor: Cumhuriyet University

Brief Summary

This study aims to investigate (I) the effectiveness of motion-controlled video game-based VR exercises on pain, fatigue, functional capacity, mood, and quality of life in patients with PCC, and (II) to determine whether they are superior to conventional exercise.

Detailed Description

79 individuals aged 18-65 years who were diagnosed with COVID-19 with a PCR test result in an oropharyngeal or nasopharyngeal swab sample taken more than 90 days ago and who had PCC symptoms for at least eight weeks were included. Patients with PCC who had been hospitalized, had signs of pneumonia or organ failure, had suffered an acute myocardial infarction or orthopedic surgery within the last 2 years, had cardiovascular system diseases such as uncontrolled hypertension, arrhythmia, or cardiac insufficiency, had known chronic respiratory system diseases, those with conditions causing widespread pain such as fibromyalgia syndrome, those with primary any neurological system diseases, or those unable to mobilize for any reason were excluded from the study.

The same physiatrist systematically evaluated the sociodemographic data, medical history including the time elapsed since the diagnosis of COVID-19, the duration of PCC symptoms, and outcome measures (fatigue level, pain intensity, general health status, emotional state, functional capacity) through face-to-face interviews at the hospital, and recorded in a standardized form.

Study Timeline

• Study First Submitted: 2021-07-28
• Study First Submitted QC: 2021-07-29
• Study Start: 2021-07-30
• Study First Posted: 2021-07-30
• Primary Completion: 2022-02-27
• Study Completion: 2022-02-27
• Status Verified: 2025-09
• Last Update Submitted: 2025-09-02
• Last Update Posted: 2025-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 79

Inclusion Criteria

• diagnosed with COVID-19 by polymerase chain reaction from an oropharyngeal or nasopharyngeal swab sample more than 90 days ago, and who had PCC symptoms for at least eight weeks

Exclusion Criteria

• have been hospitalized due to COVID-19,
• have developed pneumonia or organ failure findings.
• have had an acute myocardial infarction in the last 2 years,
• have cardiovascular system disease such as uncontrolled hypertension, arrhythmia, aneurysm, cardiac failure,
• have undergone fracture or orthopedic surgery in the last 2 years,
• have a known chronic respiratory system disease,
• have widespread pain such as fibromyalgia syndrome

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
visual Analogue Scale	8th week

Secondary Outcome Measures

Name	Time	Method
hospital anxiety and depression scale-Anxiety	0th and 8th week
Fatigue severity scale	0th and 8th week
6 minutes walking test	0th and 8th week
hospital anxiety and depression scale-Depression	0th and 8th week
Short Form-12	0th and 8th week

Trial Locations

Locations (1)

Sivas Cumhuriyet University; Sivas, Turkey (Türkiye)