Phyllantus niruri mother tincture in non alcoholic fatty liver disease

Not yet recruiting

• Conditions: Liver disorders in diseases classified elsewhere,

• Registration Number: CTRI/2022/07/044256
• Lead Sponsor: Dr Amit

Brief Summary

Non alcoholic fatty liver disease is a worldwide issue and one of the most prevapent liver illness. The increase prevalence and risk of progression of disease demands therapeutic attention. With this intension, we plan to assess the effectiveness of phyllanthus niruri Mother tincture in  patients with non alcoholic fatty liver disease.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-07-21
• Study Start: 2022-07-27

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• Age: 18-60 years ii.
• Self reported cases of non-alcoholic fatty liver disease.
• Patients with BMI more than 25kg/m2.
• Patients having Alanine aminotransferase (ALT) >40 U/L and Aspartate aminotransferase (AST)/ALT ratio >0.8 to < 1.
• Ultrasound abdomen showing fatty liver.
• Non alcoholics or consumption of less than 20 gm and 30 gm of alcohol per day in women and men respectively.
• Both sexes.
• Patients volunteering.

Exclusion Criteria

• Patients unwilling to take part or not giving consent to join the study.
• Diagnosed cases of systemic diseases, psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life or any organ failure.
• Known cases of endocrine disorders including Cushing’s syndrome or history of long term steroid intake or any other secondary causes of fatty liver.
• Pregnancy and lactation.
• Substance abuse and/ or dependence.
• Self reported immune-compromised state.
• Undergoing homoeopathic treatment for any chronic disease within the last 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Resolution of fatty liver on USG abdomen. ii. Improvement in liver enzymes (AST, ALT).	All the outcome measures will be assessed at Baseline (0 month) and after 3 months.

Secondary Outcome Measures

Name	Time	Method
36-Item Short-Form Health Survey (SF-36). ii. Change in body mass index.

Trial Locations

Locations (1)

RBTS Govt Homoeopathic Medical college and Hospital; 🇮🇳 Muzaffarpur, BIHAR, India

RBTS Govt Homoeopathic Medical college and Hospital

🇮🇳Muzaffarpur, BIHAR, India

DR Amit

Principal investigator

7765802619

amitrisdth@gmail.com