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Comparison of general and spinal anesthesia on postoperative delirium in elderly patients undergoing total knee replacement

Not Applicable
Conditions
Mental and behavioural disorders
Registration Number
KCT0006441
Lead Sponsor
Jeonbuk National University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

elderly patient, more than 65 years, undergoing total knee arthroplasty

Exclusion Criteria

1) psychotic disorder (schizophrenia, seizure, Parkinson's disease, dementia)
2) severe bradycardia (<45 bpm), sick sinus syndrome, 2nd or 3rd degree AV block)
3) severe hepatic dysfunction 4) severe renal dysfunction
5) recent history of stroke within 6 months 6) alcohol or other drug abuse
7) difficulty of communication 8) ASA PS 4 or more
9) preoperative K-MMSE score less than 20

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Develoment of postoperative delirium
Secondary Outcome Measures
NameTimeMethod
Severity of postoperative delirium
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