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Clinical Trials/NCT05504993
NCT05504993CompletedNot Applicable

Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD

Ankara University1 site in 1 country92 target enrollmentStarted: January 1, 2018Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
92
Locations
1
Primary Endpoint
Frequency of AECOPD

Study Overview

Brief Summary

INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too. Comorbidity indexes can be used for recognition of comorbidities while managing COPD patients. In the present study, it is aimed to compare comorbidity indexes such as Charlson Comorbidity Index, COMCOLD and COTE in the matter of exacerbation frequency.

METHOD: Subjects hospitalized for AECOPD, admitted to the study. Exacerbation severity, frequency, further exacerbations for a 1-year period in the follow-up period and CCI, COMCOLD and COTE scores were recorded. High and low comorbidity groups were compared for AECOPD frequency, severity, and further exacerbations.

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • COPD patients
  • Admitted to the ward for AECOPD

Exclusion Criteria

  • Not giving informed consent
  • Unable to perform PFT
  • Lost to follow-up

Outcomes

Primary Outcomes

Frequency of AECOPD

Time Frame: 1 year

Frequency of AECOPD in the last one year

Secondary Outcomes

  • Having at least one severe AECOPD(1 year)
  • Frequency of AECOPD for the next one year(1 year)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Deniz Doğan Mülazimoğlu

University Lecturer

Ankara University

Study Sites (1)

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