The Use of Near Infrared Spectroscopy (NIRS) to Estimate Intracranial Pressure (ICP)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Intracranial elastance
研究概览
简要总结
The aim of this study is to determine whether we can predict the intracranial pressure using near infra-red spectroscopy
详细描述
The management of intracranial hypertension requires the presence of an intracranial pressure monitor. We are investigating whether the waveforms obtained from a near infrared spectroscopy device can predict what the intracranial pressure is non-invasively.
- Patients with intracranial hypertension who are intubated and ventilated in the ICU will be recruited
- we will record there intracranial pressure and systemic arterial pressure
- recordings from the near infrared device will be recorded and analysed off-line
- we will correlate the waveform tracings from near infrared spectroscopy and the arterial tracing
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with an intracranial pressure monitor and arterial catheter who are admitted to the ICU
排除标准
- •Less than 18 years
结局指标
主要结局
Intracranial elastance
时间窗: Participants will be followed while an arterial line and intracranial pressure monitor is present duing the ICU admission. This is expected to be an average of 5 days.
Intracranial elastance (δP/δV)will be measured by dividing the pulse pressure of an invasive arterial blood pressure by the amplitude of high frequency oscillations in the near infrared (NIR) absorbance waveforms.
次要结局
未报告次要终点
研究者
Bhiken I. Naik, MD
Assistant Professor, Anesthesiology
University of Virginia