The Use of Near Infrared Spectroscopy (NIRS) to Estimate Intracranial Pressure (ICP)
- Conditions
- Intracranial Hypertension
- Registration Number
- NCT01850069
- Lead Sponsor
- University of Virginia
- Brief Summary
The aim of this study is to determine whether we can predict the intracranial pressure using near infra-red spectroscopy
- Detailed Description
The management of intracranial hypertension requires the presence of an intracranial pressure monitor. We are investigating whether the waveforms obtained from a near infrared spectroscopy device can predict what the intracranial pressure is non-invasively.
* Patients with intracranial hypertension who are intubated and ventilated in the ICU will be recruited
* we will record there intracranial pressure and systemic arterial pressure
* recordings from the near infrared device will be recorded and analysed off-line
* we will correlate the waveform tracings from near infrared spectroscopy and the arterial tracing
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 24
Patients with an intracranial pressure monitor and arterial catheter who are admitted to the ICU
Less than 18 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intracranial elastance Participants will be followed while an arterial line and intracranial pressure monitor is present duing the ICU admission. This is expected to be an average of 5 days. Intracranial elastance (δP/δV)will be measured by dividing the pulse pressure of an invasive arterial blood pressure by the amplitude of high frequency oscillations in the near infrared (NIR) absorbance waveforms.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Virginia
🇺🇸Charlottesville, Virginia, United States