The Use of Near Infrared Spectroscopy (NIRS) to Estimate Intracranial Pressure (ICP)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Intracranial Hypertension
- Sponsor
- University of Virginia
- Enrollment
- 24
- Locations
- 1
- Primary Endpoint
- Intracranial elastance
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The aim of this study is to determine whether we can predict the intracranial pressure using near infra-red spectroscopy
Detailed Description
The management of intracranial hypertension requires the presence of an intracranial pressure monitor. We are investigating whether the waveforms obtained from a near infrared spectroscopy device can predict what the intracranial pressure is non-invasively. * Patients with intracranial hypertension who are intubated and ventilated in the ICU will be recruited * we will record there intracranial pressure and systemic arterial pressure * recordings from the near infrared device will be recorded and analysed off-line * we will correlate the waveform tracings from near infrared spectroscopy and the arterial tracing
Investigators
Bhiken I. Naik, MD
Assistant Professor, Anesthesiology
University of Virginia
Eligibility Criteria
Inclusion Criteria
- •Patients with an intracranial pressure monitor and arterial catheter who are admitted to the ICU
Exclusion Criteria
- •Less than 18 years
Outcomes
Primary Outcomes
Intracranial elastance
Time Frame: Participants will be followed while an arterial line and intracranial pressure monitor is present duing the ICU admission. This is expected to be an average of 5 days.
Intracranial elastance (δP/δV)will be measured by dividing the pulse pressure of an invasive arterial blood pressure by the amplitude of high frequency oscillations in the near infrared (NIR) absorbance waveforms.