Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer

AdventHealth Translational Research Institute6 个研究点分布在 1 个国家目标入组 219 人2023年6月1日

适应症Colonic Neoplasms

干预措施Aerobic exercise Progressive stretching

概览

阶段: 不适用
干预措施: Aerobic exercise
疾病 / 适应症: Colonic Neoplasms
发起方: AdventHealth Translational Research Institute
入组人数: 219
试验地点: 6
主要终点: Chemotherapy Relative Dose Intensity
状态: 招募中
最后更新: 3个月前

概览研究者入排标准研究组 & 干预措施结局指标研究点相似试验

概览

简要总结

To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.

注册库

clinicaltrials.gov

开始日期

2023年6月1日

结束日期

2027年5月1日

最后更新

3个月前

研究类型

Interventional

研究设计

Parallel

性别

All

研究者

发起方

AdventHealth Translational Research Institute

责任方

Principal Investigator

主要研究者

Justin Brown

Senior Investigator

AdventHealth Translational Research Institute

入排标准

入选标准

•Age ≥18 years
•Histologically confirmed stage II or III colon cancer
•Completed surgical resection with curative intent
•Plan to initiate chemotherapy
•Engage in \<60 minutes per week of moderate- to vigorous-intensity structured aerobic exercise
•No planned major surgery during the study period
•Readiness to exercise, as determined by a modified version of the Physical Activity Readiness Questionnaire
•Can walk 400 meters
•Can read and speak English
•Ability to provide written informed consent

排除标准

•Evidence of metastatic colon cancer
•Concurrently actively treated other (non-colon) cancer
•Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks
•Currently participating in another study with competing outcomes
•Any other condition that, in the opinion of the investigator, would preclude participation or successful compliance with the protocol
•Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol