Efficiency of Transcutaneous Electrical Acupoint Stimulation(TEAS) With Single Acupoint or Two Acupoints for Postoperative Nausea and Vomiting in Laparoscopic Operation: A Single Center, Randomized, Double-blinded, Controlled Clinical Trial

wangqiang1 site in 1 country180 target enrollmentDecember 2015

ConditionsPostoperative Nausea and Vomiting

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Postoperative Nausea and Vomiting
Sponsor: wangqiang
Enrollment: 180
Locations: 1
Primary Endpoint: The incidence of postoperative nausea and vomiting
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This is a single center, randomized, double-blinded, controlled clinical trial.The purpose of this study is to compare the effect of TEAS pretreatment with single acupoint or two acupoints for postoperative nausea and vomiting in patients undergoing laparoscopic operation.

Detailed Description

Patients were randomly assigned to four groups, receiving TEAS 30 minutes before induction.The stimulation was applied until the end of the operation. Postoperative nausea and vomiting was recorded 30 minute, 2 hour, 6 hour and 24 hour after the operation. The adverse events were recorded as well.

Registry

clinicaltrials.gov

Start Date

December 2015

End Date

October 2016

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

wangqiang

Responsible Party

Sponsor Investigator

Principal Investigator

wangqiang

Professor

Xijing Hospital

Eligibility Criteria

Inclusion Criteria

•Aged 18 to 65 years old
•Scheduled for general anesthesia
•BMI index is between 18 to 30
•Informed consented

Exclusion Criteria

•Hypertension that is not controlled
•Severe hepatic or renal dysfunction
•Ever had received electrical stimulation treatment
•Severe systemic infection
•With contraindications to the use of TEAS, such as skin damage or infection at the acupoints
•For any reason one can not cope with the studies, such as the following:
•language comprehension, mental illness
•Participate in the other clinical trial 3 month before the enrollment

Outcomes

Primary Outcomes

The incidence of postoperative nausea and vomiting

Time Frame: within 24 hours after operation

Secondary Outcomes

Change of concentration of serum 5-HT(intraoperative)
Change of concentration of serum dopamine(intraoperative)
Incidence of other postoperative complications(30minutes, 2hours, 6hours and 24 hours after operation)
Postoperative nausea and vomiting（PONV） score(30minutes, 2hours, 6hours and 24 hours after operation)
Visual Analogue Scale (VAS) pain score in PACU(30 minutes after operation)