Effectiveness of Pumpkin Seed Extract on Improving Blood Sugar Level in Subhealth Subjects

Not Applicable

Recruiting

• Conditions: Metabolic Disease; Diabetes
• Interventions: Dietary Supplement: Placebo; Dietary Supplement: Pumpkin seed extract (High dose); Dietary Supplement: Pumpkin seed extract (Low dose)

• Registration Number: NCT05738655
• Lead Sponsor: Greenyn Biotechnology Co., Ltd.

Brief Summary

This randomized, double-blind, placebo-controlled, and parallel clinical study aims to investigate the effectivness of a pumpkin seed extract on blood sugar management in subhealth people.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-02-01
• Study First Submitted QC: 2023-02-12
• Study First Posted: 2023-02-22
• Study Start: 2023-03-01
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-21
• Last Update Posted: 2024-02-23
• Primary Completion: 2024-09-30
• Study Completion: 2024-10-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Fasting blood sugar levels from 100 to 125 mg/dL
• Glycated hemoglobin levels from 5.7 to 6.4%
• 2-hour OGTT levels from 140 to 199 mg/dL

Exclusion Criteria

• Pregnant women or preparing for pregnancy.
• Lactating women.
• Women gave birth 6 months before the study.
• Poor kindy funciton
• Severe cardiovascular or other chronic diseases
• Patients with type I or II diabetes
• Poor compliance
• Alcohol abuser
• Using anti-diabetic or weight managent supplements
• Blood transfusion three months before the study
• Pumpkin seed allergy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo group	Placebo	Placebo capsule, one capsule/day (300 mg/day) for 3 months
High dose	Pumpkin seed extract (High dose)	Pumpkin seed extract capsule, two capsules/day (600 mg/day) for 3 months
Low dose	Pumpkin seed extract (Low dose)	Pumpkin seed extract capsule, one capsule/day (300 mg/day) for 3 months

Primary Outcome Measures

Name	Time	Method
Biochemical analysis	Baseline up to 12 weeks	Changes in incremental area under the curve for glucose for 60 pariticpants will be analyzed between baseline and week 12.
Hormone analysis	Baseline up to 12 weeks	Changes in adiponectin levels of 60 pariticpants will be analyzed between baseline and week 12.

Trial Locations

Locations (1)

WanFang Hospital; 🇨🇳 Taipei, Taiwan