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Clinical Trials/NCT04031521
NCT04031521
Withdrawn
Not Applicable

Near-infrared Spectroscopy in Sickle Cell Pediatric Patients During Pain Crisis and After Recovery

Children's National Research Institute1 site in 1 countryJune 26, 2019
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ConditionsSickle Cell Disease

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sickle Cell Disease
Sponsor
Children's National Research Institute
Locations
1
Primary Endpoint
Tissue oxygenation
Status
Withdrawn
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Endothelial dysfunction contributes to vaso-occlusion and acute pain in sickle cell disease. Near infrared spectroscopy (NIRS) technology can measure tissue oxygenation and endothelial function. The main objective of this study is to study the natural history of tissue muscle oxygenation using NIRS in pediatric sickle cell subjects experiencing acute pain and pediatric sickle cell patients in steady-state.

Registry
clinicaltrials.gov
Start Date
June 26, 2019
End Date
September 3, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Children's National Research Institute
Responsible Party
Principal Investigator
Principal Investigator

Suvankar Majumdar

Chief of Hematology

Children's National Research Institute

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Tissue oxygenation

Time Frame: 6 months

Secondary Outcomes

  • Nitric oxide(6 months)

Study Sites (1)

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