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BVS Implantation in Patients With Variant Angina and MODerate Coronary Artery Disease

Phase 4
Withdrawn
Conditions
Angina Pectoris, Variant
Interventions
Device: BVS+OMT
Registration Number
NCT02932553
Lead Sponsor
Seung-Jung Park
Brief Summary

The purpose of this study is to determine whether BVS(Bioresorbable Vascular Scaffold) implantation with optimal medical therapy can improve the outcome of patients with variant angina and moderate coronary artery disease.

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Age 19 and more
  • Vasospastic angina diagnosed by provocation test including ergonovine provocation coronary angiography or ergonovine echocardiogram
  • No-ischemia producing moderate coronary artery disease(stenosis>50%, FFR>0.8)
Exclusion Criteria
  • Ischemic coronary lesion
  • Organic heart disease associated with myocardial ischemia or sudden cardiac death
  • History of percutaneous coronary intervention
  • Cerebrovascular diseases or peripheral disease
  • NYHA III and IV
  • Cardiac pacemaker or implantable defibrillator
  • Pregnancy or breast feeding
  • Life expectancy less than 2 years

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
BVS and OMTBVS+OMTOptimal medical treatment + BVS implantation
Primary Outcome Measures
NameTimeMethod
Composite of all cause death, myocardial infarction, and angina-related hospitalization2year
Secondary Outcome Measures
NameTimeMethod
Variant angina2year

by Ergonovine test

Stroke2year
Cardiac death2year
Angina-related hospitalization2year
All cause death2year
Repeat revascularization2year
Scaffold thrombosis2year
Myocardial infarction2year
Composite event of death or myocardial infarction2year
Composite event of cardiac death or myocardial infarction2year

Trial Locations

Locations (1)

Asan Medical Center

🇰🇷

Seoul, Korea, Republic of

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