Randomized controlled clinical trial to evaluate the efficacy of Jalaukavacharana (Leech therapy) in the management of Indralupta w.s.r. to Alopecia areata.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Symptoms like 1) Hairfall
研究概览
简要总结
Hair disorder cause negative impact towards the individuals and their quality of life. Indralupta is a Kshudraroga characterized by patchy loss of hair. It can be correlated with Alopecia Areata (AA) an autoimmune disorder characterized by the appearance of non scarring bald patches affecting the hair bearing areas of the body especially on scalp without any clinical signs of inflammation. Scalp is the most common site of involvement. AA can affect any age group. The usual pattern of hairloss is oval or round and can be correlated with Indralupta in Ayurveda.
Indralupta (Alopecia) a dermatological disorder is of great concerns to male, female as well as children too, which can also cause psychological stress. Tendency of hair fall has been increased since last two decades and hair loss in children comes to approximately 3% of all pediatric cases. Ayurveda is effective and harmless treatment for this disease. Sushruta has mentioned Indralupta as Raktapradoshaja Vikara. Pitta associated with Vata gets lodge in Romakupa and causes hairfall, later on kaphadosha associated with Rakta causes obstruction to the hair roots & restricts the regrowth. Raktamokshana is a technical term employed to denote a para surgical procedure to expel out the vitiated blood from Selected areas of the body, by specific methods. Acharya Sushruta propounds practical guidelines for bloodletting and claims it as most effective therapy in half of the body ailments. Among various methods for bloodletting such as Jalaukavacharana karma, Pracchhana. Karma & Siravedha karma, Jalaukavacharana karma (Leech therapy) is considered as the ideal method to expel out the vitiated blood safely, quickly & effectively. Jalaukavcharan helps in draining the vitiated Rakta, in turn plays an important role in samprapti vighatana of Indralupta.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients showing classical symptoms and sign of Indralupta as described in ayurvedic samhitas.
- •Bald patch present only on scalp.
- •Bald patch size upto 3cm.
- •Upto 4 bald patches.
- •Patients between the age of 18-40 years.
- •Patients will be selected who are willing to give informed consent and ready to comply with protocol.
- •Patients will be selected irrespective of gender, marital status, religion, educational and economical status.
排除标准
- •Patients are not willing.
- •Pregnant and lactating mothers.
- •Psychological disorders
- •Patients under the age of 18 and above 40years.
- •Patients with Bleeding disorders.
- •Patients with chronic Anemia.
- •Patients diagnosed with AIDS, HbsAg.
- •Bald patch present on body other than scalp.
- •Bald patch size more than 3cm.
- •Bald patch more than
- •Patients having serious dermatological disorder of scalp.
结局指标
主要结局
Symptoms like 1) Hairfall
时间窗: 7 days, 15 days, 21 days after starting treatment
2) Smooth patches on scalp
时间窗: 7 days, 15 days, 21 days after starting treatment
will be decreased and control over Indralupta with reference to Alopecia areata
时间窗: 7 days, 15 days, 21 days after starting treatment
次要结局
- Decrease in Symptoms of Indralupta(18 Months)
研究者
Dr Shweta Bandu Pandhare
Dr VJD Gramin Ayurved Mahavidyalaya Patur Akola
