Microbiological Comparative Study Between Single Maxillary Denture Fabricated From Rapid Heat Cured Resin and Conventional Acrylic Resin Modified by Titanium Dioxide Nanoparticles
试验速览
- 阶段
- 不适用
- 入组人数
- 2
- 主要终点
- Microbiological investigation: Count of anaerobic bacteria on the fitting surface of denture by (CFU) unit
研究概览
简要总结
Cross over design the investigator divide participants to two groups group (A) will receive rapid heat cured denture base material and group (b) will receive the acrylic denture modified by titanium dioxide nanoparticles and after washout period alternatively group (a) will receive the acrylic denture modified by titanium dioxide nanoparticles AND group (b) will receive rapid heat cured denture base material the investigator will take swaps from dentures to count the anaerobic bacteria.
详细描述
First the investigator will take primary impression, and pour it obtain primary cast, then will fabricate special tray an take secondary impression and obtain master cast after that duplication of master cast will be done the investigator will make cross over design.and divide participants to two groups group (A) will receive rapid heat cured denture base material and group (b) will receive the acrylic denture modified by titanium dioxide nanoparticle and after washout period alternatively group (a) will receive the acrylic denture modified by titanium dioxide nanoparticle AND group (b) will receive rapid heat cured denture base material the investigator will take swaps from the different dentures to count the anaerobic bacteria by (CFU).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Completely edentulous maxillary arch and partially dentate mandibular arch with adequate interarch space.
- •The edentulous ridges should be covered by firm healthy mucosa. 3-Angle class I maxillomandibular relation. 4-Healthy and cooperative patient
排除标准
- •Patients with bad habits as severe clenching or bruxism, drug or alcohol addiction, moderate or heavy smoking (greater than 10 cigarettes per day).
- •Previous history of radiotherapy or chemotherapy.
- •Any skeletal problem dictates surgical intervention
研究组 & 干预措施
patients take titanium dioxide denture
patients will receive titanium dioxide denture (made from conventional acrylic resin modified by titanium dioxide nanoparticles ) for 1 month in the initial phase of the trial then in the later phase after one month they will receive( rapid heat cured acrylic resin)denture
干预措施: titanium dioxide denture (Other)
patients take titanium dioxide denture
patients will receive titanium dioxide denture (made from conventional acrylic resin modified by titanium dioxide nanoparticles ) for 1 month in the initial phase of the trial then in the later phase after one month they will receive( rapid heat cured acrylic resin)denture
干预措施: rapid heat denture (Other)
patients take rapid heat denture
patients will receive rapid heat denture for 1 month in the initial phase of the trial then in the later phase patients will receive titanium dioxide denture (made from conventional acrylic resin modified by titanium dioxide nanoparticles )
干预措施: titanium dioxide denture (Other)
patients take rapid heat denture
patients will receive rapid heat denture for 1 month in the initial phase of the trial then in the later phase patients will receive titanium dioxide denture (made from conventional acrylic resin modified by titanium dioxide nanoparticles )
干预措施: rapid heat denture (Other)
结局指标
主要结局
Microbiological investigation: Count of anaerobic bacteria on the fitting surface of denture by (CFU) unit
时间窗: 6 months
Microbiological investigation: Count of anaerobic bacteria on the fitting surface of denture by (CFU) unit
次要结局
未报告次要终点
研究者
mohamed mabrouk abd Elmawla mahmoud
Principal Investigator
Cairo University