NCT00263406已完成2 期
Pathophysiological Mechanisms of Hepatopulmonary Influence in the Fontan Circulation
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Duration of the pleural drainage in the first two postoperative weeks
研究概览
简要总结
Randomisation between postoperative administration of an ACE-inhibitor or not.
详细描述
Children that are undergoing elective surgery for the creation of a Fontan circulation will be randomised to postoperative administration of an ACE-inhibitor or not.
Determination of aldosteron, renine and ADH in serum preoperatively and 1h, 12h and 5 days postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 1 Month 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All consecutive children with a univentricular heart disease undergoing elective surgery for creation of a Fontan circulation
- •Parents have agreed with the study after informed consent
排除标准
- •Urgent / Emergent surgery
- •Preoperative use of an ACE-inhibitor
结局指标
主要结局
Duration of the pleural drainage in the first two postoperative weeks
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
Unknown
1 期
Prevention of Liver Damage During Liver SurgeryLiver TumorsNCT00845689Ludwig-Maximilians - University of Munich
撤回
4 期
Anesthetic Agents and Acute Kidney Injury After Liver Resection SurgeryHepatomaCholangiocarcinomaGallbladder NeoplasmsHepatocellular CarcinomaNCT02174575Tokyo Medical and Dental University
Unknown
2 期
P2 Study of Postoperative Interferon/Fluorouracil vs Cisplatin/Fluorouracil for Hepatocellular Carcinoma.Hepatocellular CarcinomaNCT01834963Kansai Hepatobiliary Oncology Group66
已完成
2 期
A Trial of Adjuvant Transarterial Chemoembolization (TACE) for Preventing Tumor Recurrence After Liver ResectionHepatocellular CarcinomaNCT00820053Eastern Hepatobiliary Surgery Hospital450
Unknown
1 期
Anti-recurrence Treatment of Postresection on HCC Patients With MVI Presence and Over-expression of ASPHHepatocellular CarcinomaNCT02587884Eastern Hepatobiliary Surgery Hospital180