Role of Vitamin C hydrocortisone and thiamine in critically sick patients (sepsis and septic shock)
Phase 3
- Conditions
- Health Condition 1: null- patients with a diagnosis of sepsis and septic shock and lactate level more than 2 mmol/l
- Registration Number
- CTRI/2018/08/015193
- Lead Sponsor
- Sher i Kashmir Institute of Medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with a primary diagnosis of sepsis or septic shock.
Patients with a Lactate level of > 2 mmol/L
Exclusion Criteria
Patients less than < 18 years of age.
Pregnant patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 2.The primary aim is to study the hospital survival between the treatment and control groups.Timepoint: Outcome will be assesed at two time points <br/ ><br>1. In hospital mortality <br/ ><br>2. 30 day mortality
- Secondary Outcome Measures
Name Time Method 3.Secondary outcomes are duration of vasopressor therapy, requirement for renal replacement therapy in patients with Acute Kidney Injury and the change in serum lactate and the SOFA score over the first 72 hours.Timepoint: at day 1 day 2 day 3 day 4 of hospital stay