effect of Ultrasound-Guided Internal Heat Acupuncture for Alleviating Posterior Lumbar Nerve Pain and Modulating Serum IL1-ß, TNF-a, and PGE2 Levels.

Phase 1

• Conditions: Posterior Lumbar Nerve Pain.; Posterior Lumbar Nerve Pain; M54. 16

• Registration Number: IRCT20231026059863N1
• Lead Sponsor: The First People's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients aged between 18-65 years diagnosed with PLNP and reporting a pain level of at least 4 on a 10-point visual analog scale (VAS) were eligible for the study.

Exclusion Criteria

Exclusion criteria included pregnancy, current use of anti-inflammatory medications, history of spinal surgery, and contraindications to acupuncture

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Primary Outcome: Pain severity was assessed using a 10-point visual analog scale (VAS) at baseline, after the 4-week intervention period, and during follow-up visits. Timepoint: 4 weeks. Method of measurement: 1.Primary Outcome: Pain severity was assessed using a 10-point visual analog scale (VAS).

Secondary Outcome Measures

Name	Time	Method
Secondary Outcomes: Serum levels of IL1ß, TNF-a, and PGE2 were measured before and after the treatment period using established biochemical assays. Timepoint: 4 weeks. Method of measurement: Secondary Outcomes: Serum levels of IL1ß, TNF-a, and PGE2 were measured before and after the treatment period using established biochemical assays.