Participants without Type 2 Diabetes who are Overweight.
- Conditions
- Health Condition 1: E136- Other specified diabetes mellituswith other specified complications
- Registration Number
- CTRI/2020/04/024660
- Lead Sponsor
- Eli Lilly and Company India Pvt Ltd
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Body mass Index (BMI) â�¥30 kilograms per square meter (kg/m�²), or â�¥27 kg/m�² and previous diagnosis with at least one of the following comorbidities: hypertension, dyslipidemia, obstructive sleep apnea, cardiovascular disease
History of at least one unsuccessful dietary effort to lose body weight
Diabetes mellitus
Change in body weight greater than 5 kg within 3 months prior to starting study
Obesity induced by other endocrinologic disorders or monogenetic or syndromic forms of obesity
History of pancreatitis
Family or personal history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN-2)
History of significant active or unstable major depressive disorder (MDD) or other severe psychiatric disorder within the last 2 years
Any lifetime history of a suicide attempt
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percent Change from Baseline in Body Weight <br/ ><br>Percentage of Participants who Achieve �5% Body Weight ReductionTimepoint: Baseline, Week 72 <br/ ><br>Week 72
- Secondary Outcome Measures
Name Time Method