Bedside Tissue Oxygenation Monitoring With Noninvasive Jugular Venous Oximetry
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Accuracy of digital pulse oximetry
研究概览
简要总结
The goal of this observational study is to find out if researchers can measure oxygen consumption in the body without having to draw blood from lines in arteries and central veins.
Participants will undergo measurements of arterial blood oxygen saturation using both finger and neck pulse oximeters.
详细描述
TOUCAN-1 is a study to estimate the accuracy and precision of pulse oximetry as a noninvasive tool for oxygen consumption measurement. Researchers will use a pair of commercially-available, noninvasive pulse oximeters to estimate the oxygen saturation of blood in the internal jugular vein, and compare it to the directly measured oxygen saturation in sampled jugular blood. Researchers will then measure the arterial oxygen saturation in a finger, and compare it to the directly measured oxygen saturation in sampled radial arterial blood.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inpatient at the University of Wisconsin University Hospital
- •Has an internal jugular venous central line
- •Has a radial arterial line
排除标准
- •Currently receiving extracorporeal membrane oxygenation (ECMO)
- •Currently receiving continuous renal replacement therapy (CRRT/CVVH)
- •All usable lumens of the participant's jugular catheter are in use, and interruption of any medical or therapy through any lumen would, in the view of the primary care team, compromise the participant's care.
- •Jugular venous catheter is not functional or position is not confirmed by radiography
- •Arterial cannula is not functional
- •Known history of sickle cell anemia or other hemoglobinopathy
- •Therapy with any of the following medications:
- •Nitroprusside
- •Hydroxocobalamin
- •Indocyanine green
- •Norepinephrine
- •Vasopressin
- •Epinephrine
- •Any other medication or therapy that, in the judgement of the study investigators, may affect the accuracy and precision of the noninvasive oximetry results
结局指标
主要结局
Accuracy of digital pulse oximetry
时间窗: Through study completion, approximately 20 minutes
Difference in the standard deviation of the arteriovenous saturation difference comparing noninvasive photoplethysmography to invasive blood sampling and oximetry
Accuracy of jugular pulse oximetry
时间窗: Through study completion, approximately 20 minutes
Difference in the standard deviation of the arteriovenous saturation difference comparing noninvasive photoplethysmography to invasive blood sampling and oximetry
次要结局
未报告次要终点