A clinical trial to study effect of two drugs lignocaine alone and in combination with dexamethasone on prpofol injection pai
Not Applicable
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: null- Propofol injection pain
- Registration Number
- CTRI/2018/02/011747
- Lead Sponsor
- Dr Chetna Umrigar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA status I, II
Patients who required general anaesthesia
Exclusion Criteria
1.ASA status III, IV, V
2.Hypersensitivity reaction to study drug, soyabean oil, glycerol, egg lecithin
3.Pregnant or lactating patients
4.Patients with history of chronic pain with neurologic, psychiatric, cardiac, renal or liver disease or taking sedative or analgesic preoperatively
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method (1) Withdrawal response score(2) Verbal rating score <br/ ><br>(3) Behavioral signsTimepoint: Pain intensity will be evaluated during 10 second pause up to 120seconds before induction of anaesthesia
- Secondary Outcome Measures
Name Time Method pulse, NIBP, SP02, ECGTimepoint: Hemodynamic data will be recorded as basal ,after premedication ,pulse and spo2 at every 10 seconds interval for 60 seconds after injecting study drug ,after releasing cuff ,induction and every 5 minutes for 20 min.;Subjects will be contacted for 24â??h following surgery and questioned about pain, edema, wheal, flare response or swelling at the injection site.Timepoint: 24 hours after surgery